解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The effects of topical application of Rafflesia hasseltii buds and flowers extract on the rate of wound healing and histology of healed wound were assessed. Four groups of adult male Sprague Dawley rats were experimentally wounded in the posterior neck area. A thin layer of blank placebo was applied topically to wound...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.09-17
更新日期:2009-11-01 00:00:00
abstract::Nutritional and immunological status of patients with obstructive jaundice is usually severely altered, with high mortality rates. The n-3 polyunsaturate fatty acids (PUFA), particularly eicosapentaenoic acid (EPA, 20:5 n-3), posess potent immunomodulatory activities. Thus, our aim was to compare the plasma phospholip...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.09-54
更新日期:2009-11-01 00:00:00
abstract::It has been reported that levels of soluble intercellular adhesion molecule-1 (ICAM-1) in the blood are elevated in hepatocellular carcinoma patients. In the present study, serial observations of the localization of ICAM-1 in the liver were made by light and electron microscopy in rats with carcinogen-induced cancer. ...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.08-247
更新日期:2009-09-01 00:00:00
abstract::The present study was conducted in order to determine whether oxidative stress during aging involves dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis in association with the emergence of cognitive deficits. When young rats were subjected to oxidative stress in the form of hyperoxia, thiobarbituric acid rea...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.09-33
更新日期:2009-09-01 00:00:00
abstract::Oxidative stress (OS) has been implicated as one of the major underlying mechanisms behind many acute and chronic diseases. However, the measurement of free radicals or their end products is complicated. Isoprostanes, derived from the non-enzymatic peroxidation of arachidonic acid are now considered to be reliable bio...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.08-266
更新日期:2009-07-01 00:00:00
abstract::Anticancer drugs have been reported to damage the intestinal mucosa. We evaluated the effects of caloric intake on the mucosal morphology and immune cells in rats treated with 5-fluorouracil (5-FU). Rats were received a liquid diet plus 5-FU treatment for 8 days as follows: Low calorie group (25 kcal/day with 5-FU), N...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.08-264
更新日期:2009-07-01 00:00:00
abstract::Effects of soy isoflavones, genistein and daidzein, on the hepatic gene expression profile and indices for lipid metabolism were compared in rats. In the first experiment (Expt. 1), animals were fed diets containing 2 g/kg of either genistein or daidzein, or a control diet free of isoflavone for 14 days. In the second...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.08-211
更新日期:2009-05-01 00:00:00
abstract::We previously reported that the plasma level of endotoxin and colonic expression of IgA in the mouse increased with obstructive jaundice induced by bile duct ligation (BDL). To elucidate the mechanism of the BDL-induced increase, we analyzed the effect of BDL on intestinal flora in wild type and inducible nitric oxide...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.08-213
更新日期:2009-03-01 00:00:00
abstract::Ubiquinol-10 (QH(2)), the reduced form of Coenzyme Q(10) (CoQ(10)) serves as a potent antioxidant of lipid membranes. Because many antioxidants reveal potent anti-inflammatory effects, the influence of QH(2) on lipopolysaccharide (LPS)-induced pro-inflammatory cytokines and chemokines were determined in the human mono...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.08-182
更新日期:2009-01-01 00:00:00
abstract::The effects of inulin on the microbial composition and faecal characteristics in 36 healthy, formula-fed infants (average age 7.7 months) given 3 different daily dosages of native inulin (0.75 g/day, 1.00 g/day, and 1.25 g/day) were studied. At all levels of inulin consumption, a significant (p<0.05) reduction of pote...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.2008055
更新日期:2008-11-01 00:00:00
abstract::Proton pump inhibitors (PPIs) are now commonly used for the treatment of acid related diseases such as peptic ulcer and reflux esophagitis. Because of their ability to produce direct inhibition of the proton pump, PPIs provide more sustained increase of the gastric pH than H(2)-receptor (H(2)R) antagonists. Diverse re...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.2008028
更新日期:2008-05-01 00:00:00
abstract::This study aimed to consider the significance of breast milk in preventing oxidative stress by comparing total antioxidant capacity (TAC) in breast milk and formula milk for premature infants, demonstrating the relationship between TAC in breast milk and postnatal age in days. We used the biological anti-oxidant poten...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.2008019
更新日期:2008-03-01 00:00:00
abstract::Previously, we identified four metabolites of (-)-epicatechin in blood and urine: (-)-epicatechin-3'-O-glucuronide (E3'G), 4'-O-methyl-(-)-epicatechin-3'-O-glucuronide (4'ME3'G), (-)-epicatechin-7-O-glucuronide (E7G), and 3'-O-methyl-(-)-epicatechin-7-O-glucuronide (3'ME7G) (Natsume et al. Free Radical Biol. Med. 34, ...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.2008008
更新日期:2008-01-01 00:00:00
abstract::Anti-peptic and anti-inflammatory actions of ecabet sodium might be beneficial in either improving gastritis or relieving dyspeptic symptoms. This study was designed to evaluate the clinical efficacy of ecabet sodium on dyspeptic symptoms and to elucidate the molecular mechanism attributable to symptom relief in patie...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.2007022
更新日期:2007-11-01 00:00:00
abstract::We examined the effects of citric acid and l-carnitine administration on physical fatigue. In a double-blind, placebo-controlled, 3-way crossover study, 18 healthy volunteers were randomized to oral citric acid (2,700 mg/day), l-carnitine (1,000 mg/day), or placebo for 8 days. The fatigue-inducing physical task consis...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.2007032
更新日期:2007-11-01 00:00:00
abstract::Neutrophil accumulation within epithelial crypts and in the intestinal mucosa directly correlates with clinical disease activity and epithelial injury in ulcerative colitis (UC). Current advances have defined the mechanisms by which neutrophils are activated or migrate across mucosal epithelia. A better understanding ...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.2007003
更新日期:2007-07-01 00:00:00
abstract::The amount of phosphorus contained in food as food additives is currently increasing and a high intake of phosphorus can cause various diseases. To determine the effects of a prolonged high phosphorus diet, here we investigated the phosphorus and calcium balance and expression of type IIa sodium-dependent phosphate tr...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.40.221
更新日期:2007-05-01 00:00:00
abstract::There has been considerable public and scientific interest in the use of phytochemicals derived from dietary components to combat human diseases. They are naturally occurring substances found in plants. Ferulic acid (FA) is a phytochemical commonly found in fruits and vegetables such as tomatoes, sweet corn and rice b...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.40.92
更新日期:2007-03-01 00:00:00
abstract::Although atopic dermatitis is known to be closely associated with food antigens, the actual changes in the gastrointestinal tract have not been clarified. The aim of this study was to investigate the macroscopic and histological features of the large intestine in patients with atopic dermatitis. We studied 15 outpatie...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.40.24
更新日期:2007-01-01 00:00:00
abstract::A Using streptozotocin-induced diabetic rats, we examined the effects of zinc supplementation and insulin treatment on the metabolic availability of vitamin A. All diabetic animals exhibited an elevated plasma glucose (>18 mmol/liter) level within 48 h of intravenous streptozotocin injection. The untreated diabetic ra...
journal_title:Journal of clinical biochemistry and nutrition
pub_type: 杂志文章
doi:10.3164/jcbn.19.165
更新日期:1995-01-01 00:00:00